Measurement of uric acid, urea and creatinine in plasma of hypertensive patients in Khartoum Sudan

Abstract

This study is descriptive analytical cross sectional study, aimed to measure plasma uric acid, urea and creatinine levels in Sudanese hypertensive patients. Blood samples were collected from sixty patients with hypertension (study group) and twenty five samples from healthy, normotensive subjects (control group) from ribat university Hospital during the period from December 2017 to January 2018.Plasma levels of uric acid, urea and creatinine were measured in each group. Results showed that in hypertensive patients, the plasma uric acid mean level was (8.5_+1.6 mg/dl), urea mean level was (40 _+13.4mg/dl) and for creatinine (1.14_+0.28mg/dl) were significantly higher than normotensive. (P.value< 0.03), (p.value< 0.001) and (p.value<0.05) respectively. The study illustrated a moderately weak positive correlation between uric acid and systolic and diastolic measurements of hypertension patient to. (r=0.58, p.value 0.000). Renal function and uric acid should regularly measuredIn hypertensive patients especially in those with prolonged period of the disease